Biochemical features of the MHC-related protein 1 consistent with an immunological function.

@article{Miley2003BiochemicalFO,
  title={Biochemical features of the MHC-related protein 1 consistent with an immunological function.},
  author={Michael J. Miley and Steven M. Truscott and Yik Yeung Lawrence Yu and Susan Gilfillan and Daved H. Fremont and Ted H. Hansen and Lonnie P Lybarger},
  journal={Journal of immunology},
  year={2003},
  volume={170 12},
  pages={6090-8}
}
MHC-related protein (MR)1 is an MHC class I-related molecule encoded on chromosome 1 that is highly conserved among mammals and is more closely related to classical class I molecules than are other nonclassical class I family members. In this report, we show for the first time that both mouse and human MR1 molecules can associate with the peptide-loading complex and can be detected at low levels at the surface of transfected cells. We also report the production of recombinant human MR1… CONTINUE READING