Biochemical effects of dietary intakes of different broccoli samples. I. Differential modulation of cytochrome P-450 activities in rat liver, kidney, and colon.

@article{Vang2001BiochemicalEO,
  title={Biochemical effects of dietary intakes of different broccoli samples. I. Differential modulation of cytochrome P-450 activities in rat liver, kidney, and colon.},
  author={Ole Vang and Henrik Frandsen and Kristian Tage Hansen and J. N. S\orensen and Hilmer S\orensen and Ole Bj\orn Andersen},
  journal={Metabolism: clinical and experimental},
  year={2001},
  volume={50 10},
  pages={1123-9}
}
Modulation of xenobiotic metabolism, including cytochrome P-450 (CYP) enzyme activities, due to dietary intakes of cruciferous vegetables, has been described in animals and humans, and the induction of CYP1A enzymes is suggested mainly to be related to the content of indolyl glucosinolates in these vegetables. The aim of the present study was to evaluate the effects on specific CYP activities of various broccoli samples containing different levels of glucosinolates. Groups of rats were fed 1 of… CONTINUE READING
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