Biochemical differences in tumorigenic and nontumorigenic cells measured by Raman and infrared spectroscopy.

@article{Mourant2005BiochemicalDI,
  title={Biochemical differences in tumorigenic and nontumorigenic cells measured by Raman and infrared spectroscopy.},
  author={Judith R. Mourant and Kurt W Short and Susan Carpenter and Nagapratima Kunapareddy and Leslie Coburn and Tamara M. Powers and James P. Freyer},
  journal={Journal of biomedical optics},
  year={2005},
  volume={10 3},
  pages={031106}
}
Both infrared and Raman spectroscopies have the potential to noninvasively estimate the biochemical composition of mammalian cells, although this cannot be unambiguously determined from analysis approaches such as peak assignment or multivariate classification methods. We have developed a fitting routine that determines biochemical composition using basis spectra for the major types of biochemicals found in mammalian cells (protein, DNA, RNA, lipid and glycogen), which is shown to be robust and… CONTINUE READING

From This Paper

Topics from this paper.
12 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…