Biochemical characterization of mIgM− variants of the murine B-cell lymphoma, WEHI 279.1

@article{Sibley1983BiochemicalCO,
  title={Biochemical characterization of mIgM− variants of the murine B-cell lymphoma, WEHI 279.1},
  author={Carol Hopkins Sibley and Rebecca Andrews-Wagner},
  journal={Immunogenetics},
  year={1983},
  volume={17},
  pages={189-202}
}
The membrane immunoglobulin M (m1gM) of a B lymphocyte serves as a receptor for its cognate antigen. Our aim is to elucidate the structure and function of this membrane-bound receptor. The first step is to determine the requirements for proper membrane placement of IgM. We have used mIgM-positive B lymphocyte tumors from which we isolated mIgM negative variants by immunoselection. We report here the initial characterization of mIgM-variants isolated by repeated cycles of selection of the murine… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 33 references

The intracellular ratio of the membrane to secreted form of immunoglobulin m heavy chain is a measure of the developmental stage of B cell lymphomas

  • Sibley, H C., Mar, A H., Mains, E P.
  • Dev. Genetics
  • 1982

Similar Papers

Loading similar papers…