Biochemical characterization of human epidermal retinol dehydrogenase 2.

@article{Lee2009BiochemicalCO,
  title={Biochemical characterization of human epidermal retinol dehydrogenase 2.},
  author={Soonbong Lee and Olga Belyaeva and Natalia Y Kedishvili},
  journal={Chemico-biological interactions},
  year={2009},
  volume={178 1-3},
  pages={182-7}
}
The mRNA encoding a putative human enzyme named Epidermal Retinol Dehydrogenase 2 (RDH-E2) was found to be significantly elevated in psoriatic skin [Y. Matsuzaka, K. Okamoto, H. Tsuji, T. Mabuchi, A. Ozawa, G. Tamiya, H. Inoko, Identification of the hRDH-E2 gene, a novel member of the SDR family, and its increased expression in psoriatic lesion, Biochem. Biophys. Res. Commun. 297 (2002) 1171-1180]. This finding led the authors to propose that RDH-E2 may be involved in the pathogenesis of… CONTINUE READING

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