Biochemical characterization of human collagenase-3.

  title={Biochemical characterization of human collagenase-3.},
  author={Vera Kn{\"a}uper and Carlos L{\'o}pez-Ot{\'i}n and Brenden Smith and Gordon Knight and Gillian Murphy},
  journal={The Journal of biological chemistry},
  volume={271 3},
The cDNA of a novel matrix metalloproteinase, collagenase-3 (MMP-13) has been isolated from a breast tumor library (Freije, J. M. P., Dicz-Itza, I., Balbin, M., Sanchez, L. M., Blasco, R., Tolivia, J., and López-Otin, C. (1994) J. Biol. Chem. 269, 16766-16773), and a potential role in tumor progression has been proposed for this enzyme. In order to… CONTINUE READING