Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40.

@article{BraeschAndersen1989BiochemicalCA,
  title={Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40.},
  author={Sten Braesch-Andersen and Staffan Paulie and Hannu Koho and H Nika and Pontus Aspenstr{\"o}m and Peter Perlmann},
  journal={Journal of immunology},
  year={1989},
  volume={142 2},
  pages={562-7}
}
The Ag CDw40 (p50, Bp50) is a phosphoprotein expressed on the surface of both B lymphocytes and on certain malignant cell types of nonhemopoietic origin. Antibodies to this Ag have been shown to act as a potent co-mitogen for B cells. In order to elucidate the function of this Ag, we have now investigated some of its biochemical characteristics as well as the relationship of B cell derived CDw40 to that derived from urinary bladder carcinoma (transitional cell carcinoma, TCC) cells. CDw40 from… CONTINUE READING
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