Biochemical characterisation of the actin-binding properties of utrophin.

@article{Moores2000BiochemicalCO,
  title={Biochemical characterisation of the actin-binding properties of utrophin.},
  author={Carolyn A Moores and John Kendrick-Jones},
  journal={Cell motility and the cytoskeleton},
  year={2000},
  volume={46 2},
  pages={116-28}
}
Utrophin is a large ubiquitously expressed cytoskeletal protein that is important for maturation of vertebrate neuromuscular junctions. It is highly homologous to dystrophin, the protein defective in Duchenne and Becker muscular dystrophies. Utrophin binds to the actin cytoskeleton via an N-terminal actin-binding domain, which is related to the actin… CONTINUE READING