Biochemical characterisation and immunohistochemical localisation of the secretogranin II-derived peptide EM66 in the hypothalamus of the jerboa (Jaculus orientalis): modulation by food deprivation.

@article{Boutahricht2005BiochemicalCA,
  title={Biochemical characterisation and immunohistochemical localisation of the secretogranin II-derived peptide EM66 in the hypothalamus of the jerboa (Jaculus orientalis): modulation by food deprivation.},
  author={Mohammed Boutahricht and Johann Guillemot and Mait{\'e} Montero-Hadjadje and S Bellafqih and Seloua El Ouezzani and Abdelilah Lamrani Alaoui and Laurent Yon and Hubert Vaudry and Y Anouar and Rabia Magoul},
  journal={Journal of neuroendocrinology},
  year={2005},
  volume={17 6},
  pages={372-8}
}
The neuroendocrine protein secretogranin II is the precursor of several neuropeptides, including secretoneurin and a novel 66-amino acid peptide, EM66, the sequence of which has been highly conserved across the vertebrae phylum. The presence of EM66 has been detected in the adult and fetal human adrenal gland, as well as the rat pituitary and adrenal glands. The present study aimed to explore a possible neuroendocrine role of EM66 by analysing its occurrence and distribution within the jerboa… CONTINUE READING

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