Biochemical changes induced by pyrphenoxone in the lens of rabbits and rats.

@article{Drago1995BiochemicalCI,
  title={Biochemical changes induced by pyrphenoxone in the lens of rabbits and rats.},
  author={F. Drago and V. D’Agata and V. Marino and A. Marino and G. Blasco},
  journal={Pharmacological research},
  year={1995},
  volume={31 5},
  pages={
          325-9
        }
}
The xanthomatine analogue, pyrphenoxone, which is known to diminish the incidence of cataract in animals and in man, was applied in two different in vivo models of cataract induced in rabbits by tryptophan-free dietary regimen and in rats by hypergalactosemic diet. The drug was also applied at different concentrations in an in vitro model of cataract. It was found that soluble proteins and sulphurated amino acids of the lens in all in vivo and in vitro models of cataract were higher after… Expand

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