Biochemical changes in hairless mouse skin collagen after chronic exposure to ultraviolet-A radiation.

@article{Kligman1991BiochemicalCI,
  title={Biochemical changes in hairless mouse skin collagen after chronic exposure to ultraviolet-A radiation.},
  author={Lorraine H. Kligman and M Gebre},
  journal={Photochemistry and photobiology},
  year={1991},
  volume={54 2},
  pages={233-7}
}
Evidence is mounting that UV-B and UV-A radiation affect skin differently in responses as diverse as erythema and elastosis. We found in this study that collagen metabolism was also differentially affected. Albino hairless mice were irradiated with two UV-A sources: (1) UVASUN 3000 (340-400 nm) for cumulative exposures of 4000 and 8000 J/cm2; (2) a xenon solar simulator filtered to provide full spectrum UV-A (320-400 nm) and long wavelength UV-A (335-400 nm) for cumulative exposures of 3000 and… CONTINUE READING

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