Biochemical changes in a porcine model of acute pancreatitis.

  title={Biochemical changes in a porcine model of acute pancreatitis.},
  author={S P Marenberg and John N. A. Lott and Burkhard Pflug and W E Kibbey and Larry C. Carey},
  journal={Clinical chemistry},
  volume={24 6},
Pancreatitis was induced in 11 miniature pigs by infusing a bile salt-trypsin solution into the pancreatic duct. Seven animals served as sham-operated controls. Serum ionized calcium, total calcium, albumin, total protein, inorganic phosphorus, urea nitrogen, magnesium, insulin, glucagon, and hematocrit were determined every six to 12 h over a period of one week in both test and control animals. We observed significant decreases in ionized and total calcium, modest decreases in albumin, and… CONTINUE READING