Biochemical basis of the effect of chondroitin sulphate on osteoarthritis articular tissues

@article{Monfort2008BiochemicalBO,
  title={Biochemical basis of the effect of chondroitin sulphate on osteoarthritis articular tissues},
  author={Jordi Monfort and J. P. Pelletier and Nat{\`a}lia Garcia-Giralt and Johanne Martel-Pelletier},
  journal={Annals of the Rheumatic Diseases},
  year={2008},
  volume={67},
  pages={735 - 740}
}
Osteoarthritis is a chronic disease characterised by irreversible damage to joint structures, including loss of articular cartilage, osteophyte formation, alterations in the subchondral bone and synovial inflammation. Pain, functional disability and impairment of health-related quality of life are major complaints in patients with osteoarthritis. Several compounds have been investigated for their positive effects on the relief of clinical symptoms and improvement of structural changes in… 
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