Biochemical basis of regulation of human copper-transporting ATPases.

@article{Lutsenko2007BiochemicalBO,
  title={Biochemical basis of regulation of human copper-transporting ATPases.},
  author={Svetlana Lutsenko and Erik S Leshane and Ujwal Shinde},
  journal={Archives of biochemistry and biophysics},
  year={2007},
  volume={463 2},
  pages={
          134-48
        }
}
Copper is essential for cell metabolism as a cofactor of key metabolic enzymes. The biosynthetic incorporation of copper into secreted and plasma membrane-bound proteins requires activity of the copper-transporting ATPases (Cu-ATPases) ATP7A and ATP7B. The Cu-ATPases also export excess copper from the cell and thus critically contribute to the homeostatic control of copper. The trafficking of Cu-ATPases from the trans-Golgi network to endocytic vesicles in response to various signals allows for… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 40 CITATIONS

The rules of variation: amino acid exchange according to the rotating circular genetic code.

  • Journal of theoretical biology
  • 2010
VIEW 11 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Molecular mechanisms of copper homeostasis.

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Copper homeostasis in human mammary epithelial cells

VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

Similar Papers

Loading similar papers…