Biochemical approaches for discovering protein-protein interactions.

  title={Biochemical approaches for discovering protein-protein interactions.},
  author={J{\'a}n A. Miernyk and Jay J. Thelen},
  journal={The Plant journal : for cell and molecular biology},
  volume={53 4},
Protein-protein interactions or protein complexes are integral in nearly all cellular processes, ranging from metabolism to structure. Elucidating both individual protein associations and complex protein interaction networks, while challenging, is an essential goal of functional genomics. For example, discovering interacting partners for a 'protein of unknown function' can provide insight into actual function far beyond what is possible with sequence-based predictions, and provide a platform… CONTINUE READING

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