Biochemical approach to the detection and monitoring of metastatic bone disease: What do we know and what questions need answers?


Metastatic spread to bones frequently occurs in several types of cancer diseases, in particular breast, prostate, and lung cancer. Infiltration of bone by tumour cells is a source of several complications including severe bone pain, spinal cord compression, hypercalcemia, pathologic fractures, all reducing quality of life and worsening prognosis. Therefore… (More)
DOI: 10.1007/s10555-006-9024-0

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