Biochemical and structural properties of mouse kynurenine aminotransferase III.

@article{Han2009BiochemicalAS,
  title={Biochemical and structural properties of mouse kynurenine aminotransferase III.},
  author={Qian Han and Howard Robinson and Tao Cai and Danilo A. Tagle and Junsuo S Li},
  journal={Molecular and cellular biology},
  year={2009},
  volume={29 3},
  pages={784-93}
}
Kynurenine aminotransferase III (KAT III) has been considered to be involved in the production of mammalian brain kynurenic acid (KYNA), which plays an important role in protecting neurons from overstimulation by excitatory neurotransmitters. The enzyme was identified based on its high sequence identity with mammalian KAT I, but its activity toward kynurenine and its structural characteristics have not been established. In this study, the biochemical and structural properties of mouse KAT III… CONTINUE READING

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