Biochemical and morphological characterization of an intracellular membrane compartment containing AMPA receptors.

@article{Lee2001BiochemicalAM,
  title={Biochemical and morphological characterization of an intracellular membrane compartment containing AMPA receptors.},
  author={S H Tony Lee and Juli G. Valtschanoff and Viktor N. Kharazia and Richard Weinberg and Morgan Sheng},
  journal={Neuropharmacology},
  year={2001},
  volume={41 6},
  pages={680-92}
}
AMPA receptors cycle rapidly in and out of the postsynaptic membrane, while NMDA receptors are relatively immobile. Changing the distribution of AMPA receptors between intracellular and surface synaptic pools is an important means of controlling synaptic strength. However, little is known about the intracellular membrane compartments of neurons that contain AMPA receptors. Here we describe biochemical and morphological characteristics of an intracellular pool of AMPA receptors in rat brain. By… CONTINUE READING
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