Biochemical and molecular mechanisms regulating apoptosis

@article{Saini1998BiochemicalAM,
  title={Biochemical and molecular mechanisms regulating apoptosis},
  author={Kulvinder Singh Saini and Neal I. Walker},
  journal={Molecular and Cellular Biochemistry},
  year={1998},
  volume={178},
  pages={9-25}
}
In eukaryotes, the regulation of tissue cell numbers is a critical homeostatic objective that is achieved through tight control of apoptosis, mitosis and differentiation. While much is known about the genetic regulation of cell growth and differentiation, the molecular basis of apoptosis is less well understood. Genes involved in both cell proliferation and apoptosis reflect the role of some stimuli in both of these processes, the cell response depending on the overall cellular milieu. Recent… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 125 REFERENCES

Shrinkage necrosis: a distinct mode of cellular death.

  • The Journal of pathology
  • 1971
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1996

Apoptosis and APC in colorectal tumorigenesis.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1996