Biochemical and molecular analysis of the mammalian cytoplasmic dynein intermediate chain.

Abstract

Cytoplasmic dynein is a multisubunit protein complex responsible for the intracellular movement of membranous organelles and other cargo along microtubules. The heavy chains contain the motor domains, while the intermediate chain and other subunits are important for binding to cargo. There are at least five different intermediate chain polypeptides, the… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.