Biochemical and mechanical properties of subchondral bone in osteoarthritis.

  title={Biochemical and mechanical properties of subchondral bone in osteoarthritis.},
  author={Allen J. Bailey and Jason Peter Mansell and Trevor J. Sims and Xavier Banse},
  volume={41 3-4},
The subchondral bone has long been known to thicken in osteoarthritis. However, recent evidence has demonstrated that the turnover of the bone is increased several fold, and further suggests that the thickening occurs prior to degradation of the articular cartilage, indicating that it plays a role in the pathogenesis of osteoarthritis. The mechanical and biochemical properties of the subchondral bone are therefore of particular interest in any attempt to determine the nature of the factors… CONTINUE READING

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