Biochemical and histological changes in the small intestine of mice with dextran sulfate sodium colitis.

@article{Yazbeck2011BiochemicalAH,
  title={Biochemical and histological changes in the small intestine of mice with dextran sulfate sodium colitis.},
  author={Roger Yazbeck and Gordon Stanley Howarth and Ross N. Butler and Mark S. Geier and Catherine A Abbott},
  journal={Journal of cellular physiology},
  year={2011},
  volume={226 12},
  pages={3219-24}
}
The dextran sulfate sodium (DSS) model of colitis has been commonly utilized in mice to assess novel treatments for ulcerative colitis. Recent studies have indicated that morphological and biochemical changes extend to the small intestine (SI). This study aimed to characterize histological and biochemical changes in the SI during DSS colitis in wild-type (WT) and DPIV knock-out (DPIV(-/-) ) mice treated with saline or the DPIV inhibitors, Ile-Pyrr-(2-CN)*TFA or Ile-Thia. Groups (n = 10) of DPIV… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…