Biochemical and histochemical evaluation of glycosaminoglycans in brain tumors induced in rats by nitrosourea derivatives

@article{Mauro1983BiochemicalAH,
  title={Biochemical and histochemical evaluation of glycosaminoglycans in brain tumors induced in rats by nitrosourea derivatives},
  author={Alessandro Mauro and Antonio Bertolotto and Maria Teresa Giordana and Maria Luisa Magrassi and Antonio Migheli and Davide Schiffer},
  journal={Journal of Neuro-Oncology},
  year={1983},
  volume={1},
  pages={299-306}
}
The occurrence, distribution and concentration of GAGs in ENU and MNU experimental brain tumors induced in the rat are reported. GAGs have been histochemically studied by Alcian Blue methods; they have been quantified and qualitatively evaluated by electrophoresis of brain extracts. The pattern of GAGs in normal rats is consistent with the data of the literature. No GAG accumulation precedes the tumor development. Early neoplastic proliferations, oligodendroglial and mixed glial microtumors are… CONTINUE READING

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The occurrence , distribution and concentration of GAGs in ENU and MNU experimental brain tumors induced in the rat are reported .
The occurrence , distribution and concentration of GAGs in ENU and MNU experimental brain tumors induced in the rat are reported .
In large tumors , GAGs are histochemically demonstrable in the honey - comb areas of oligodendrogliomas and in peripheral infiltration areas of polymorphic gliomas .
In large tumors , GAGs are histochemically demonstrable in the honey - comb areas of oligodendrogliomas and in peripheral infiltration areas of polymorphic gliomas .
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