Biochemical and bioinformatic analysis of the myosin-XIX motor domain.

@article{Adikes2013BiochemicalAB,
  title={Biochemical and bioinformatic analysis of the myosin-XIX motor domain.},
  author={Rebecca C. Adikes and William C T Unrath and Christopher M Yengo and Omar A. Quintero},
  journal={Cytoskeleton},
  year={2013},
  volume={70 5},
  pages={
          281-95
        }
}
Mitochondrial dynamics are dependent on both the microtubule and actin cytoskeletal systems. Evidence for the involvement of myosin motors has been described in many systems, and until recently a candidate mitochondrial myosin transport motor had not been described in vertebrates. Myosin-XIX (MYO19) was predicted to represent a novel class of myosin and had previously been shown to bind to mitochondria and increase mitochondrial network dynamics when ectopically expressed. Our analyses… CONTINUE READING
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