Biochemical analysis of related, independently arising histocompatibility mutants: bm17 and KB-98 enlarge the “bg series” of H-2Kb mutants

@article{Pfaffenbach1990BiochemicalAO,
  title={Biochemical analysis of related, independently arising histocompatibility mutants: bm17 and KB-98 enlarge the “bg series” of H-2Kb mutants},
  author={Gertrude M. Pfaffenbach and Roger W. Melvold and Stanley G. Nathenson},
  journal={Biochemical Genetics},
  year={1990},
  volume={28},
  pages={433-441}
}
The “bg” series of MHC mutations is the most prevalent type of mutations of Kb in C57BL/6 mice screened by reciprocal tail skin grafting. The basis for identification of this series of mutations is the incompatibility of grafts between the parental B6 and the mutant. This series takes the longest to reciprocally reject the skin grafts. The series can be subdivided into “bg 1” and “bg 2” groups based on Kb-restricted recognition of virus-infected mutant target cells. The biochemical basis for… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 32 references

Spontaneous frequency of H-2 mutations

  • R. W. Melvold, H. I. Kohn
  • Transgenic Mice and Mutants in MHC Research
  • 1990

The cause of this high frequency

  • mutations, see Melvold, Kohn
  • 1989

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