Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes.

@article{Abruzzi2004BiochemicalAO,
  title={Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes.},
  author={Katharine C Abruzzi and Scott A. Lacadie and Michael Rosbash},
  journal={The EMBO journal},
  year={2004},
  volume={23 13},
  pages={2620-31}
}
The TREX complex is involved in both transcription elongation and mRNA export and is recruited to nascent transcription complexes. We have examined Yra1p, Sub2p and Hpr1p recruitment to nine genes of varying lengths and transcription frequencies. All three proteins increase from the 5' to the 3' ends of the four intronless genes examined. A modified chromatin immunoprecipitation assay that includes an RNase step indicates that Sub2p is bound to nascent RNA, Yra1p is associated with both RNA and… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
70 Citations
53 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 70 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Similar Papers

Loading similar papers…