Corpus ID: 39090599

Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle.

  title={Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle.},
  author={J. Holloszy},
  journal={The Journal of biological chemistry},
  volume={242 9},
  • J. Holloszy
  • Published 1967
  • Biology, Medicine
  • The Journal of biological chemistry
Abstract The capacity of the mitochondrial fraction from gastrocnemius muscle to oxidize pyruvate doubled in rats subjected to a strenuous program of treadmill running. Succinate dehydrogenase, reduced diphosphopyridine nucleotide dehydrogenase, DPNH cytochrome c reductase, succinate oxidase, and cytochrome oxidase activities, expressed per g of muscle, increased approximately 2-fold in hind limb muscles in response to the training. The concentration of cytochrome c was also increased 2-fold… Expand
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