Biochemical abnormalities in vitreous of humans with proliferative diabetic retinopathy.

@article{Sebag1992BiochemicalAI,
  title={Biochemical abnormalities in vitreous of humans with proliferative diabetic retinopathy.},
  author={J Sebag and Bruce B Buckingham and M. Arthur Charles and Kathrin Reiser},
  journal={Archives of ophthalmology},
  year={1992},
  volume={110 10},
  pages={1472-6}
}
Vitreous changes in diabetes can exacerbate proliferative diabetic retinopathy. These changes may be due to the effects of diabetes on vitreous collagen. Vitreous samples from 19 patients with proliferative diabetic retinopathy and 23 patients without diabetes were analyzed for collagen crosslinks, as well as for the early glycation products, glucitolyllysine and glucitolylhydroxylysine. Fluorometry was performed to measure advanced glycation end products. Vitreous collagen derived from… CONTINUE READING
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