Biochemical Methods to Analyze Wnt Protein Secretion.

  title={Biochemical Methods to Analyze Wnt Protein Secretion.},
  author={Kathrin Glaeser and Michael Boutros and Julia Christina Gross},
  journal={Methods in molecular biology},
Wnt proteins act as potent morphogens in various aspects of embryonic development and adult tissue homeostasis. However, in addition to its physiological importance, aberrant Wnt signaling has been linked to the onset and progression of different types of cancer. On the cellular level, the secretion of Wnt proteins involves trafficking of lipid-modified Wnts from the endoplasmic reticulum (ER) to Golgi and further compartments via the Wnt cargo receptor evenness interrupted. Others and we have… 
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