Biochemical Isolation of the Myddosome from Murine Macrophages.

Abstract

Ligand-induced macromolecular protein complex formation has emerged as a common means by which the innate immune system activates signal transduction pathways essential for host defense. Despite their structural divergence, key signaling molecules in diverse innate immune pathways mediate signal transduction by assembling higher-order protein complexes at… (More)
DOI: 10.1007/978-1-4939-7519-8_6

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