Biochemical, Histological, and Memory Impairment Effects of Chronic Copper Toxicity: A Model for Non-Wilsonian Brain Copper Toxicosis in Wistar Rat

@article{Pal2013BiochemicalHA,
  title={Biochemical, Histological, and Memory Impairment Effects of Chronic Copper Toxicity: A Model for Non-Wilsonian Brain Copper Toxicosis in Wistar Rat},
  author={Amit Kumar Pal and Rama Kumari Badyal and Rakesh kumar Vasishta and Savita Verma Attri and Babu Ram Thapa and Rajendra Prasad},
  journal={Biological Trace Element Research},
  year={2013},
  volume={153},
  pages={257-268}
}
Animal models of copper toxicosis rarely exhibit neurological impairments and increased brain copper accumulation impeding the development of novel therapeutic approaches to treat neurodegenerative diseases having high brain Cu content. The aim of this study was to investigate the effects of intraperitoneally injected copper lactate (0.15 mg Cu/100 g body… CONTINUE READING