Bioavailability of lithium from lithium citrate syrup versus conventional lithium carbonate tablets.

@article{Guelen1992BioavailabilityOL,
  title={Bioavailability of lithium from lithium citrate syrup versus conventional lithium carbonate tablets.},
  author={P. J. M. Guelen and Theodore J. Janssen and Theo de Witte and Tom B. Vree and K W Benson},
  journal={Biopharmaceutics & drug disposition},
  year={1992},
  volume={13 7},
  pages={503-11}
}
The bioavailability of lithium citrate syrup was compared with that of regular lithium carbonate tablets in 18 healthy male human volunteers. Blood samples were collected up to 48 h after dosing. Lithium serum concentrations were determined by means of AAS. The absorption rate following oral administration of the syrup was greater (tmax 0.8 h) than following administration of regular tablets (tmax 1.4 h). Maximum lithium serum concentrations, however, were only about 10 per cent higher after… CONTINUE READING