Bioavailability of PCBs to Male Laboratory Rats Maintained on Litters of Contaminated Soils: PCB Burden and Induction of Alkoxyresorufin O-Dealkylase Activities in Liver and Lung

@article{Fouchcourt1998BioavailabilityOP,
  title={Bioavailability of PCBs to Male Laboratory Rats Maintained on Litters of Contaminated Soils: PCB Burden and Induction of Alkoxyresorufin O-Dealkylase Activities in Liver and Lung},
  author={M. O. Fouch{\'e}court and P J Berny and J. L. Rivi{\`e}re},
  journal={Archives of Environmental Contamination and Toxicology},
  year={1998},
  volume={35},
  pages={680-687}
}
Abstract. Male rats from the Sprague-Dawley laboratory strain were maintained in the laboratory during 3 days and 1 night on litters containing a reference soil and different amounts of a soil, mainly polluted by PCBs (207 ppm expressed in Aroclor® 1254; SIII soil). Two categories of biomarkers of exposure were measured in both liver and lung of these rats: PCB burdens and activities of microsomal liver and lung cytochrome P450–dependent mono-oxygenases, namely ethoxy-, pentoxy-, and benzoxy… CONTINUE READING