Bioavailability for humans of deuterium-labeled monoglutamyl and polyglutamyl folates is affected by selected foods.

@article{Wei1996BioavailabilityFH,
  title={Bioavailability for humans of deuterium-labeled monoglutamyl and polyglutamyl folates is affected by selected foods.},
  author={M. Wei and L. Bailey and J. Toth and J. Gregory},
  journal={The Journal of nutrition},
  year={1996},
  volume={126 12},
  pages={
          3100-8
        }
}
  • M. Wei, L. Bailey, +1 author J. Gregory
  • Published 1996
  • Chemistry, Medicine
  • The Journal of nutrition
  • Dietary folate exists mainly as polyglutamyl forms that require deconjugation by Zn-dependent pteroylpolyglutamate hydrolase prior to intestinal absorption. Because deconjugation by pteroylpolyglutamate hydrolase is an essential step in the absorption of dietary polyglutamyl folates, factors influencing the deconjugation process may affect folate bioavailability. This study was conducted to evaluate in vivo the bioavailability of [2H4]folic acid (d4-PteGlu1) and [2H2]-pteroylhexaglutamate (d2… CONTINUE READING
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