Bioavailability and pharmacokinetics of acyclovir tablet preparation.

  title={Bioavailability and pharmacokinetics of acyclovir tablet preparation.},
  author={K H Yuen and Kok Khiang Peh and N Billa and K L Chan and W T Toh},
  journal={Drug development and industrial pharmacy},
  volume={24 2},
The bioavailability of a generic preparation of acyclovir (Avorax) was compared with the innovator product, Zovirax. Twelve healthy volunteers participated in the study, conducted according to a randomized, two-way crossover design. The preparations were compared using the parameters area under the plasma concentration time curve (AUC(0-infinity), peak plasma concentration (Cmax), and time to reach peak plasma concentration (Tmax). No statistically significant difference was observed between… CONTINUE READING

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