Bioavailability and pharmacokinetics of a praziquantel bolus in kingfish Seriola lalandi.

  title={Bioavailability and pharmacokinetics of a praziquantel bolus in kingfish Seriola lalandi.},
  author={Lincoln Tubbs and Malcolm Drummond Tingle},
  journal={Diseases of aquatic organisms},
  volume={69 2-3},
Oral praziquantel (PZQ) preparations have recently been investigated for the treatment of monogeneans that infect the skin and gills of kingfish Seriola lalandi cultured in sea-cages. To evaluate an oral PZQ dosing strategy, the pharmacokinetics of a dissolved and in feed oral PZQ preparation (40 mg kg(-1) body weight) were compared with an intravenous bolus in kingfish plasma and skin using HPLC. Compared with intravenous administration, PZQ bioavailability (area under curve, AUC0-24h) was… CONTINUE READING
Highly Cited
This paper has 17 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.
8 Citations
24 References
Similar Papers


Publications citing this paper.
Showing 1-8 of 8 extracted citations


Publications referenced by this paper.
Showing 1-10 of 24 references

Efficacy of praziquantel bath treatments for monogenenean infections of the Rhinobatos typus

  • I Ernst, ID Whittington, S Corneillie, C Talbot
  • J Aquat Anim Health
  • 2002
Highly Influential
4 Excerpts

Mono - genean parasites in seacage aquaculture

  • I Ernst, ID Whittington, S Corneillie, C Talbot
  • Aust Aquacult
  • 2002
Highly Influential
4 Excerpts

abaddon in the West Australian dhufish , Glaucosoma hebraicum

  • DA Thoney
  • 2006

Effects of the gill parasite Zeuxapta seriolae ( Monogenea : Heteraxinidae ) on the amberjack Seriola dumerili Risso ( Teleostei : Carangidae )

  • K Ogawa
  • Aquaculture
  • 2004

Suscep - tibility of spotted halibut Verasper variegatus ( Pleuronectidae ) to infection by the monogenean Neobenedenia girellae ( Capsalidae ) and oral therapy trials using praziquantel

  • M Janse, Borgsteede FHM
  • Aquaculture
  • 2004

Meta - zoan parasites of yellowtail kingfish , Seriola lalandi lalandi , in New Zealand : prevalance , intensity , and site preference

  • N Sharp, BK Diggles, CW Poortenaar, TJ Willis
  • NZ J Mar FW Res
  • 2003
1 Excerpt

Praziquantel treatment of captive white - spotted eagle rays ( Aetobatus narinari ) infested with monogenean trematodes

  • KH Kim, JB Cho
  • Bull Eur Assoc Fish Pathol
  • 2003

Similar Papers

Loading similar papers…