Bioavailability and genetic prescribing

  title={Bioavailability and genetic prescribing},
  author={Joel S. Mindel},
Abstract Although oral drug bioinequivalence has been attributed to a number of causes (excipients, dosage form, variation in dissolution time, and aging) less is known about bioavailability problems of topical medications in ophthalmology. Factors that can alter drug absorption from solutions (pH, partition coefficient, container impurities, contact time, etc.) are noted, and cases in which bioavailability problems should be considered as causes of therapeutic failure are discussed. Various… CONTINUE READING

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