Bioavailability and Bioequivalence of Two Enteric-Coated Formulations of Omeprazole in Fasting and Fed Conditions

@article{VazdaSilva2005BioavailabilityAB,
  title={Bioavailability and Bioequivalence of Two Enteric-Coated Formulations of Omeprazole in Fasting and Fed Conditions},
  author={M. Vaz-da-Silva and A. Loureiro and T. Nunes and J. Maia and S. Tavares and A. Falc{\~a}o and P. Silveira and L. Almeida and P. Soares-da-Silva},
  journal={Clinical Drug Investigation},
  year={2005},
  volume={25},
  pages={391-399}
}
  • M. Vaz-da-Silva, A. Loureiro, +6 authors P. Soares-da-Silva
  • Published 2005
  • Medicine
  • Clinical Drug Investigation
  • AbstractObjective: To investigate the relative bioavailability and bioequivalence, in fasting and fed conditions, of repeated doses of two omeprazole enteric-coated formulations in healthy volunteers. Material and methods: Open label, single-centre study consisting of two consecutive randomised, two-way crossover trials (a fasting trial and a fed trial). Each trial consisted of two 7-day treatment periods in which subjects received one daily dose of the test (Ompranyt®) or reference (Mopral… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 25 CITATIONS, ESTIMATED 20% COVERAGE

    Food, physiology and drug delivery.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    FILTER CITATIONS BY YEAR

    2008
    2020

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 10 REFERENCES

    Bioequivalence evaluation of two omeprazole enteric-coated formulations in humans.

    Clinical Pharmacology of Omeprazole

    • C. Howden
    • Medicine
    • Clinical pharmacokinetics
    • 1991

    Bioavailability of 31 ( 2 ) : 969 omeprazole given in conjunction with food

    • Int J Clin Pharmacol Ther Toxicol
    • 1993

    Estudio de biodis - and the power approach for assessing the equivalence of ponibilidad relativa de dos formulaciones orales de omeprazol average bioavailability

    • Statistical approaches to establishing 8 . Note for guidance on the investigation of bioavailability and bioequivalence Drug information to the health care professional , 9 . Critérios Exigibles a los genéricos de Omeprazol . Comité de 22 nd ed . Omeprazole Systemic
    • 2002