Bioassay of tetrachloroethylene for possible carcinogenicity.

  title={Bioassay of tetrachloroethylene for possible carcinogenicity.},
  journal={National Cancer Institute carcinogenesis technical report series},
  • Published 1977 in
    National Cancer Institute carcinogenesis…
The bioassay of U.S.P.-grade tetrachloroethylene for possible carcinogenicity was conducted using Osborne-Mendel rats and B6C3F1 mice. Tetrachloroethylene in corn oil was administered by gavage at either of two dosages to groups of 50 male and 50 female animals of each species, 5 days a week, over a period of 78 weeks followed by an observation period of 32 weeks for rats and 12 weeks for mice. Initial dosage levels for the chronic bioassay were selected on the basis of a preliminary subchronic… CONTINUE READING
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