Bioassay of isophosphamide for possible carcinogenicity.

  • Published 1977 in
    National Cancer Institute carcinogenesis…


A bioassay of the anticancer drug isophosphamide for possible carcinogenicity was conducted by injecting the test chemical intraperitoneally into Sprague-Dawley rats and B6C3F1 mice. Groups of 35 rats and 35 mice of each sex were given the injections at one of two doses three times per week for 52 weeks. Doses for rats were either 6 or 12 mg/kg, and for… (More)


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