Bioassay-guided evaluation of antinociceptive properties and chemical variability of the essential oil of Hyptis fruticosa.


The composition of three samples of essential oil (EO) extracted from the leaves and flowers of Hyptis fruticosa (Lamiaceae) were investigated by GC/MS and GC-FID. The variability of the constituents and biological activity were evaluated in the oil samples. Acetic acid-induced abdominal constrictions and formalin-induced pain tests in mice were used for… (More)
DOI: 10.1002/ptr.3455


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