Bioassay for Tumor Necrosis Factors-α and β.


The realization that much of the toxicity of bacterial endotoxin resulted from production of a macrophage-derived intermediate (1) led to the isolation and cloning of tumor necrosis factor (TNF), also known as cachectin (2). Since then, much evidence has accumulated to demonstrate that TNF is of prime importance in the pathogenesis of endotoxin-related… (More)
DOI: 10.1385/1-59259-216-3:83


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