Bioanalytical procedures for determination of drugs of abuse in blood
@article{Kraemer2007BioanalyticalPF, title={Bioanalytical procedures for determination of drugs of abuse in blood}, author={T. Kraemer and L. D. Paul}, journal={Analytical and Bioanalytical Chemistry}, year={2007}, volume={388}, pages={1415-1435} }
Determination of drugs of abuse in blood is of great importance in clinical and forensic toxicology. This review describes procedures for detection of the following drugs of abuse and their metabolites in whole blood, plasma or serum: Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol, 11-nor-9-carboxy-Δ9-tetrahydrocannabinol, 11-nor-9-carboxy-Δ9-tetrahydrocannabinol glucuronide, heroin, 6-monoacetylmorphine, morphine, morphine-6-glucuronide, morphine-3-glucuronide, codeine… CONTINUE READING
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References
SHOWING 1-10 OF 109 REFERENCES
Concentration profiles of cocaine, pyrolytic methyl ecgonidine and thirteen metabolites in human blood and urine: determination by gas chromatography-mass spectrometry.
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 2005
- 54
Advances in analytical toxicology: the current role of liquid chromatography–mass spectrometry in drug quantification in blood and oral fluid
- Medicine, Chemistry
- Analytical and bioanalytical chemistry
- 2005
- 128
Enantioselective quantitation of the ecstasy compound (R)- and (S)-N-ethyl-3,4-methylenedioxyamphetamine and its major metabolites in human plasma and urine.
- Chemistry, Medicine
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2003
- 29
The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry.
- Chemistry, Medicine
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2005
- 121
Toxicokinetics of Amphetamines: Metabolism and Toxicokinetic Data of Designer Drugs, Amphetamine, Methamphetamine, and Their N-Alkyl Derivatives
- Chemistry, Medicine
- Therapeutic drug monitoring
- 2002
- 206
Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry.
- Chemistry, Medicine
- Journal of mass spectrometry : JMS
- 2003
- 158
Drugs of Abuse Monitoring in Blood for Control of Driving Under the Influence of Drugs
- Medicine
- Therapeutic drug monitoring
- 2002
- 99
- PDF
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites in human samples including the catechol-type metabolite (3,4-dihydroxymethamphetamine).
- Chemistry, Medicine
- Drug metabolism and disposition: the biological fate of chemicals
- 2004
- 76
- PDF
Determination of drugs of abuse and their metabolites in human plasma by liquid chromatography-mass spectrometry. An application to 156 road fatalities.
- Chemistry, Medicine
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2006
- 54
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites by gas chromatography/mass spectrometry.
- Chemistry, Medicine
- Rapid communications in mass spectrometry : RCM
- 2003
- 41