Bioadhesive ultrasound for long-term continuous imaging of diverse organs

@article{Wang2022BioadhesiveUF,
  title={Bioadhesive ultrasound for long-term continuous imaging of diverse organs},
  author={Chonghe Wang and Xiaoyu Chen and Liu Wang and Mitsutoshi Makihata and Hsiao-Chuan Liu and Tao Zhou and Xuanhe Zhao},
  journal={Science},
  year={2022},
  volume={377},
  pages={517 - 523}
}
Continuous imaging of internal organs over days could provide crucial information about health and diseases and enable insights into developmental biology. We report a bioadhesive ultrasound (BAUS) device that consists of a thin and rigid ultrasound probe robustly adhered to the skin via a couplant made of a soft, tough, antidehydrating, and bioadhesive hydrogel-elastomer hybrid. The BAUS device provides 48 hours of continuous imaging of diverse internal organs, including blood vessels, muscle… 

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References

SHOWING 1-10 OF 39 REFERENCES

Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs

Lights, Sound, Images Optical microscopy can readily image thin samples such as cells, but thicker samples, such as tissue, are more difficult to image directly, because of the multiple scattering of

Soft Microfluidic Assemblies of Sensors, Circuits, and Radios for the Skin

Experimental and theoretical approaches for using ideas in soft microfluidics, structured adhesive surfaces, and controlled mechanical buckling to achieve ultralow modulus, highly stretchable systems that incorporate assemblies of high-modulus, rigid, state-of-the-art functional elements are described.

Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging

It is demonstrated in vivo that ultrasound imaging at ultrafast frame rates provides an analogue to optical localization microscopy by capturing the transient signal decorrelation of contrast agents—inert gas microbubbles that modify the microvascular blood flow in animals and humans using ultrasound.

A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy.

G graphene doped with gold and combined with a gold mesh has improved electrochemical activity over bare graphene, sufficient to form a wearable patch for sweat-based diabetes monitoring and feedback therapy and can be thermally actuated to deliver Metformin and reduce blood glucose levels in diabetic mice.

Monitoring of the central blood pressure waveform via a conformal ultrasonic device

The design and operation of an ultrasonic device that is conformal to the skin and capable of capturing blood pressure waveforms at deeply embedded arterial and venous sites is described, which enables the non-invasive, continuous and accurate monitoring of cardiovascular events from multiple body locations.

Soft wearable devices for deep-tissue sensing

Wearable devices with skin-like mechanical properties enable continuous monitoring of the human body. However, wearable device design has mainly focused on recording superficial signals from the skin

An epidermal patch for the simultaneous monitoring of haemodynamic and metabolic biomarkers.

A non-invasive skin-worn device for the simultaneous monitoring of blood pressure and heart rate via ultrasonic transducers and of multiple biomarkers via electrochemical sensors, optimized so that it provides mechanical resiliency and flexibility while conforming to curved skin surfaces.

Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays.

In healthy volunteers, the prototype skin-conformal ultrasonic phased array can be used to monitor Doppler spectra from cardiac tissues, record central blood flow waveforms and estimate cerebral blood supply in real time.

Dry double-sided tape for adhesion of wet tissues and devices

A new strong, biocompatible and biodegradable double-sided tape can adhere to wet tissues and devices through a mechanism involving rapid water removal from the surface, swift hydrogen and electrostatic interactions, and covalent bonding.

Imaging Tools for the Developmental Biologist: Ultrasound Biomicroscopy of Mouse Embryonic Development

This state-of-the-art review will discuss the development and potential of ultrasound biomicroscopy as a tool for the in vivo imaging and phenotyping of both cardiac and non-cardiac organ systems in the early developing mouse.