Bioactivity-guided isolation of polyacetylenes with inhibitory activity against NO production in LPS-activated RAW264.7 macrophages from the rhizomes of Atractylodes macrocephala.

@article{Yao2014BioactivityguidedIO,
  title={Bioactivity-guided isolation of polyacetylenes with inhibitory activity against NO production in LPS-activated RAW264.7 macrophages from the rhizomes of Atractylodes macrocephala.},
  author={Chun-mei Yao and Xiu-wei Yang},
  journal={Journal of ethnopharmacology},
  year={2014},
  volume={151 2},
  pages={791-9}
}
ETHNOPHARMACOLOGICAL RELEVANCE The rhizome of Atractylodes macrocephala (Compositae) is one of the most well-known traditional Chinese medicine in China, Japan and Korea, which has a long history of use for the treatment of splenic asthenia, edema, anorexia, and excessive perspiration, etc. As active compounds of anti-inflammatory activity of this medicinal plant have not been fully elucidated, the aim of this study was to isolate and identify the active constituents inhibiting nitric oxide (NO… CONTINUE READING
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