Bioactivity-guided isolation of antiproliferative compounds from Centaurea jacea L.

@article{Forg2012BioactivityguidedIO,
  title={Bioactivity-guided isolation of antiproliferative compounds from Centaurea jacea L.},
  author={P. Forg{\'o} and I. Zupk{\'o} and J. Moln{\'a}r and A. Vasas and G. Dombi and J. Hohmann},
  journal={Fitoterapia},
  year={2012},
  volume={83 5},
  pages={
          921-5
        }
}
Bioassay-guided fractionation of the chloroform extract of Centaurea jacea L. afforded the isolation of cirsiliol, apigenin, hispidulin, eupatorin, isokaempferide, axillarin, centaureidin, 6-methoxykaempferol 3-methyl ether, trachelogenin, cnicin, 4'-acetylcnicin and three aliphatic glucose diesters, including the new natural product 1β-isobutanoyl-2-angeloyl-glucose. The structures of the compounds were established on the basis of spectroscopic analyses (UV, MS and NMR). All compounds were… Expand
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