Bioactivity-guided isolation of anticancer agents from Bauhinia kockiana Korth.

  title={Bioactivity-guided isolation of anticancer agents from Bauhinia kockiana Korth.},
  author={Yik-Ling Chew and Yau Yan Lim and Johnson Stanslas and Gwendoline Cheng Lian Ee and Joo Kheng Goh},
  journal={African journal of traditional, complementary, and alternative medicines : AJTCAM},
  volume={11 3},
  • Yik-Ling ChewY. Lim J. Goh
  • Published 29 March 2014
  • Biology, Chemistry
  • African journal of traditional, complementary, and alternative medicines : AJTCAM
BACKGROUND Flowers of Bauhinia kockiana were investigated for their anticancer properties. METHODS Gallic acid (1), and methyl gallate (2), were isolated via bioassay-directed isolation, and they exhibited anticancer properties towards several cancer cell lines, examined using MTT cell viability assay. Pyrogallol (3) was examined against the same cancer cell lines to deduce the bioactive functional group of the phenolic compounds. RESULTS The results showed that the phenolic compounds could… 

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