Bioactivity and cytotoxicity of glass and glass–ceramics based on the 3CaO·P2O5–SiO2–MgO system

  title={Bioactivity and cytotoxicity of glass and glass–ceramics based on the 3CaO·P2O5–SiO2–MgO system},
  author={J. K. M. F. Daguano and S. Rogero and M. Crovace and O. Peitl and K. Strecker and C. Santos},
  journal={Journal of Materials Science: Materials in Medicine},
  • J. K. M. F. Daguano, S. Rogero, +3 authors C. Santos
  • Published 2013
  • Medicine, Materials Science
  • Journal of Materials Science: Materials in Medicine
  • The mechanical strength of bioactive glasses can be improved by controlled crystallization, turning its use as bulk bone implants viable. However, crystallization may affect the bioactivity of the material. The aim of this study was to develop glass–ceramics of the nominal composition (wt%) 52.75(3CaO·P2O5)–30SiO2–17.25MgO, with different crystallized fractions and to evaluate their in vitro cytotoxicity and bioactivity. Specimens were heat-treated at 700, 775 and 975 °C, for 4 h. The major… CONTINUE READING
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