Bioactive substrates for human retinal pigment epithelial cell growth from elastin-like recombinamers.

@article{Singh2014BioactiveSF,
  title={Bioactive substrates for human retinal pigment epithelial cell growth from elastin-like recombinamers.},
  author={Amar K. Singh and Girish K Srivastava and Laura Mart{\'i}n and Matilde Alonso and Jc Pastor},
  journal={Journal of biomedical materials research. Part A},
  year={2014},
  volume={102 3},
  pages={
          639-46
        }
}
The aim of this study was to investigate the use of bioactive RGD-containing elastin-like recombinamers (ELR-RGDs) as a substrate that can maintain human retinal pigment epithelial cell (hRPE) phenotype and growth pattern. Results obtained are compared with previously published behavior of ARPE19 cells. The extension of these results to hRPE is required because ARPE19 cells cannot be used clinically to treat age-related macular degeneration. hRPE cells were isolated, cultured, seeded, and grown… 
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TLDR
Results should be extended to further studies with fresh human RPE cells and in vivo studies to determine whether this ELR-RGD matrix could be used as a Bruch's membrane prosthesis and carrier for transplantation of R PE cells in patients suffering with AMD.
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