Bioactive products formed in humans from fish oils.

  title={Bioactive products formed in humans from fish oils.},
  author={Carsten Skarke and Naji Alamuddin and John A. Lawson and Xuanwen Li and Jane F Ferguson and Muredach P. Reilly and Garret A. FitzGerald},
  journal={Journal of lipid research},
  volume={56 9},
Resolvins, maresins, and protectins can be formed from fish oils. These specialized pro-resolving mediators (SPMs) have been implicated in the resolution of inflammation. Synthetic versions of such SPMs exert anti-inflammatory effects in vitro and when administered to animal models. However, their importance as endogenous products formed in sufficient amounts to exert anti-inflammatory actions in vivo remains speculative. We biased our ability to detect SPMs formed in healthy volunteers by… CONTINUE READING
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